MOI IV Papers

Stindt S., Hustedt T., Dobner K., Brum A., Spitzley S., Albrecht U., Wolf S., Bock H., Fluegen G., Knoefel W., Ludwig S, Bartenschlagen R., Vucus M., Luedde T., Ehlting C. & Bode G. J. Hepatitis C Virus reprograms 1 host cell response to Interleukin-1β 2 by interfering with Inhibitor of kB-mediated signaling. Cellular and molecular gastroenterology and hepatology.

Ahor, H. S., Vivekanandan, M., Harelimana, J. D., Owusu, D. O., Adankwah, E., Seyfarth, J., Phillips, R., & Jacobsen, M. (2024). Immunopathology in human pulmonary tuberculosis: Inflammatory changes in the plasma milieu and impaired host immune cell functions. Immunology, 10.1111/imm.13761. Advance online publication. https://doi.org/10.1111/imm.13761

Ahor HS, Schulte R, Adankwah E, Harelimana JD, Minadzi D, Acheampong I, Vivekanandan MM, Aniagyei W, Yeboah A, Arthur JF, Lamptey M, Abass MK, Kumbel F, Osei-Yeboah F, Gawusu A, Debrah LB, Owusu DO, Debrah A, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M. Monocyte pathology in human tuberculosis is due to plasma milieu changes and aberrant STAT signalling. Immunology. 2023 May 23. doi: 10.1111/imm.13659. Epub ahead of print. PMID: 37219921.

Morales, J.*, Ehret, G.*, Poschmann, G., Reinicke, T., Maurya, A.K., Kröninger, L., Zanini, D., Wolters, R., Kalyanaraman, D., Krakovka, M., Bäumers, M., Stühler, K., and Nowack, E.C.M. (2023) Host-symbiont interactions in Angomonas deanei include the evolution of a host-derived dynamin ring around the endosymbiont division site. Curr Biol. 33: 28-40. https://doi.org/10.1016/j.cub.2022.11.020

Schermer B, Fabretti F, Damagnez M, Di Cristanziano V, Heger E, et al. (2020) Rapid SARS-CoV-2 testing in primary material based on a novel multiplex RT-LAMP assay. PLOS ONE 15(11): e0238612. doi.org/10.1371/journal.pone.0238612

Keitel V, Bode JG, Feldt T, Walker A, Müller L, Kunstein A, Klindt C, Killer A, Senff T, Timm J, Ostermann P, Damagnez M, Lübke N, Adams O, Schaal H, Antoch G, Neubert J, Albrecht P, Meuth S, Elben S, Mohring A, Fischer JC, Bölke E, Hoenig M, Schulz AS, Luedde T, Jensen B. Case Report: Convalescent Plasma Achieves SARS-CoV-2 Viral Clearance in a Patient With Persistently High Viral Replication Over 8 Weeks Due to Severe Combined Immunodeficiency (SCID) and Graft Failure. Front Immunol. 2021 May 3;12:645989. doi: 10.3389/fimmu.2021.645989. PMID: 34012436; PMCID: PMC8126709. https://pubmed.ncbi.nlm.nih.gov/34012436/

Walker A, Houwaart T, Finzer P, Ehlkes L, Tyshaieva A, Damagnez M, Strelow D, Duplessis A, Nicolai J, Wienemann T, Tamayo T, Kohns Vasconcelos M, Hülse L, Hoffmann K, Lübke N, Hauka S, Andree M, Däumer MP, Thielen A, Kolbe-Busch S, Göbels K, Zotz R, Pfeffer K, Timm J, Dilthey AT; German COVID-19 OMICS Initiative (DeCOI). Characterization of SARS-CoV-2 infection clusters based on integrated genomic surveillance, outbreak analysis and contact tracing in an urban setting. Clin Infect Dis. 2021 Jun 28:ciab588. doi: 10.1093/cid/ciab588. Epub ahead of print. PMID: 34181711; PMCID: PMC8406867 .https://pubmed.ncbi.nlm.nih.gov/34181711/

Harelimana JD, Ahor HS, Benner B, Hellmuth S, Adankwah E, Minadzi D, Aniagyei W, Lamptey MNK, Arthur J, Yeboah A, Abass MK, Debrah LB, Owusu DO, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M. Cytokine-induced transient monocyte IL-7Ra expression and the serum milieu in tuberculosis. Eur J Immunol. 2022 Mar 13. doi: 10.1002/eji.202149661. Epub ahead of print. PMID: 35279828.

Ostermann PN, Ritchie A, Ptok J, Schaal H. Let It Go: HIV-1 cis-Acting Repressive Sequences. J Virol. 2021 Jul 12;95(15):e0034221. doi: 10.1128/JVI.00342-21. Epub 2021 Jul 12. PMID: 33980600; PMCID: PMC8274598.

Erenburg IN, Hänsch S, Chacko FM, Hamacher A, Wintgens S, Stuhldreier F, Poschmann G, Spitz O, Stühler K, Wesselborg S, Hegemann JH, Smits SHJ, Weidtkamp-Peters S, Schmitt L. Heterologously secreted MbxA from Moraxella bovis induces a membrane blebbing response of the human host cell. Sci Rep. 2022 Oct 24;12(1):17825. doi: 10.1038/s41598-022-22480-x. PMID: 36280777; PMCID: PMC9592583.

Chacko, Feby M. and Schmitt, Lutz. "Interaction of RTX toxins with the host cell plasma membrane" Biological Chemistry, 2023. https://doi.org/10.1515/hsz-2022-0336

Kuenzel, N. A., Alcázar-Román, A. R., Saiardi, A., Bartsch, S. M., Daunaraviciute, S., Fiedler, D., & Fleig, U. (2022). Inositol pyrophosphate-controlled kinetochore architecture and mitotic entry in S. pombe. Journal of Fungi, 8(9), 933.

Tersteegen A, Sorg UR, Virgen-Slane R, Helle M, Petzsch P, Dunay IR, Köhrer K, Degrandi D, Ware CF, Pfeffer K. Lymphotoxin β Receptor: a Crucial Role in Innate and Adaptive Immune Responses against Toxoplasma gondii. Infect Immun. 2021 May 17;89(6):e00026-21. doi: 10.1128/IAI.00026-21. PMID: 33753412; PMCID: PMC8316152. https://pubmed.ncbi.nlm.nih.gov/33753412/

Wevers, C.; Höhler, M.; Alcázar-Román, A.R.; Hegemann, J.H.; Fleig, U. A Functional Yeast-Based Screen Identifies the Host Microtubule Cytoskeleton as a Target of Numerous Chlamydia pneumoniae Proteins. Int. J. Mol. Sci. 2023, 24, 7618. https://doi.org/10.3390/ijms24087618

Hoi, D. M., Junker, S., Junk, L., Schwechel, K., Fischel, K., Podlesainski, D., Hawkins, P. M. E., van Geelen, L., Kaschani, F., Leodolter, J., Morreale, F. E., Kleine, S., Guha, S., Rumpel, K., Schmiedel, V. M., Weinstabl, H., Meinhart, A., Payne, R. J., Kaiser, M., Hartl, M., Boehmelt G., Kazmaier U., Kalscheuer R., Clausen, T. (2023). Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival. Cell, S0092-8674(23)00404-X. https://doi.org/10.1016/j.cell.2023.04.009

Junk L, Schmiedel VM, Guha S, Fischel K, Greb P, Vill K, Krisilia V, van Geelen L, Rumpel K, Kaur P, Krishnamurthy RV, Narayanan S, Shandil RK, Singh M, Kofink C, Mantoulidis A, Biber P, Gmaschitz G, Kazmaier U, Meinhart A, Leodolter J, Hoi D, Jun-ker S, Morreale FE, Clausen T, Kalscheuer R, Weinstabl H, Boehmelt G. Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant myco-bacteria. Nat Commun 15, 2005 (2024). https://doi.org/10.1038/s41467-024-46218-7