Beste MOI Dissertationen
Best Doctoral Thesis of the Manchot Graduate School MOI I
Dr. Alida Schäkel
Thesis: AGC-Kinase-Netzwerk in Candida albicans
PI: Prof. Dr. Joachim F. Ernst
Dr. Alida Schäkel's doctoral thesis focused on the topic of ‘AGC kinase network in Candida albicans’. Her research findings contribute to a deeper understanding of the regulatory role of AGC kinases in the pathogenicity mechanisms of Candida.
Dr. Tim Fechner
Thesis: Charakterisierung der neuen, potentiellen Adhäsine Yaa1, Yaa2 und Yaa3 von Chlamydia pneumoniae
PI: Prof. Dr. Johannes H. Hegemann
Dr. Tim Fechtner wrote his doctoral thesis on the topic of ‘Characterization of the new potential adhesins Yaa1, Yaa2, and Yaa3 of Chlamydia pneumoniae’. The results of his research represent another important milestone on the path to developing a vaccine that is not yet available.
Best Doctoral Thesis of the Manchot Graduate School MOI II
Dr. Lasse van Wijlick
Thesis: Adaptation of the human fungal pathogen Candida albicans to host specific environmental conditions mediated by the Ace2 transcription factor
PI: Prof. Dr. Joachim Ernst
Best Doctoral Thesis of the Manchot Graduate School MOI III
Dr. Lisa Müller
Thesis: RNA: Regulatory information in human disease and viral infection
PI: Prof. Dr. Heiner Schaal
Best Doctoral Thesis of the Manchot Graduate School MOI IV
Dr. Fabienne Kocher
Thesis: RNA: Molecular Characterization of Chlamydia – Host Interactions During the Early Stages of Infection
PI: Prof. Dr. Johannes Hegemann
Dr. Fabienne Kocher was awarded for her work “Molecular Characterization of Chlamydia–Host Interactions During the Early Stages of Infection.” In her dissertation, Kocher investigated the early stages of infection by the human pathogenic bacteria Chlamydia trachomatis and Chlamydia pneumoniae at the molecular level. She demonstrated how these pathogens, which can replicate only within host cells, use specific surface proteins as well as effector proteins introduced into the host cell at an early stage. In this way, they selectively bind to human epithelial cells and manipulate their cellular structures to facilitate entry into the cell. The results of this research provide new mechanistic insights into key processes of bacterial infection and early host–pathogen interactions.